​KNOWLES RESEARCH LAB
University of Denver
​NE​WS & EVENTS​
2024
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Savannah West joined the lab as a graduate student in the Molecular and Cellular Biophysics Program.
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Elias DeWitt joined the lab as a graduate student in the Chemistry and Biochemistry program.
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We went to the annual Biophysical Society meeting in Philadelphia.
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Megan Hulser graduated with her B.S. Chemistry degree in June and heads to Boston University in the Fall.
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Andre Allen, Lyin Ghadri, and Noah Fahlin joined the lab as undergraduates.
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Alan's paper was accepted to the Biophysical Journal.
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Michelle was promoted to full professor.
2023
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Rakib Miah joined the lab as a graduate student in the Chemistry and Biochemistry Program.
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We went to the annual Biophysical Society meeting in San Diego. Brody Bills presented a poster.
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Michelle became a Faculty Mentoring Liaison for the NSF ADVANCE grant at DU.
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Zdenek graduated with his B.S. Chemistry degree in June and heads to Columbia for graduate school.
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Brody graduated with his PhD in Molecular and Cellular Biophysics and is now a postdoc at the University of Oregon.
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Alan got a job as a Research Engineer at the Knight Cancer Institute at the Oregon Health and Science University.
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Olivia Harman joined the lab and received a Summer Funding Award from the Undergraduate Research Center at DU.
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Michelle presented at the Biophysical Society's Membrane Fusion and Budding Conference in Estes Park, Colorado.
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Michelle received an NSF grant to study how Phospholipase D regulates Exosome Secretion.
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Brody's paper was accepted to Molecular Biology of the Cell.
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Michelle participated in the Facilitating Mentoring training as part of the CIMER program at the University of Wisconsin.
2022
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Melodie Nguyen joins the lab. She's a Ph.D. student in the Molecular and Cellular Biophysics Program at DU.
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Megan Hulser joined the lab (actually in 2021)
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Anarkali Mahmood, Zdeněk Otruba, Melodie Nguyen, Brody Bills, Max Palay and Alan Weisgerber submit their work on exosome secretion kinetics and tethering.
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Anarkali Mahmood defended her Ph.D.
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We went to the annual Biophysical Society meeting in San Francisco. Brody Bills and Alan Weisgerber presented posters.
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Our review paper on MVE docking and exosome secretion was accepted.
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Max Palay graduates with his B.S. Chemistry degree in June. He's off to UCSD for graduate school.
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Alan graduated with his PhD in Chemistry.
2021
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Alan published some of his recent work on dye - substrate interactions that affect measurements of molecule mobility: https://doi.org/10.1016/j.bbadva.2021.100026
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Michelle received a mid-career focused, NSF award from Molecular and Cellular Biophysics division entitled " Application of quantitative imaging methods to identify molecular components of multi-vesicular body fusion sites"
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July - Michelle and Alan submitted a paper entitled "Dye – Substrate Interactions Affect the Dynamics of Extracellularly Labeled Membrane Proteins" to BBA Advances
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Max Palay received funding for the Department of Chemistry and Biochemistry for summer research.
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Zdeněk Otruba received funding from the Undergraduate Research Center at the University of Denver.
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Undergraduate in the lab, Ellis Stice, graduated!
2020
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Michelle, Brody and Alan attended the annual Biophysical Society meeting in California. Brody and Alan presented posters on their research and Michelle spoke at a sub-group meeting.
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Michelle received funding from the NSF for Brody Bills to work with Recalibrate Solutions. The work will involve developing a lateral flow biosensor for cortisol.
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2019
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Cole Pollina received a PinS grant from the Undergraduate Research Center for research on lipid - dye interactions
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Cole Pollina won an award at the University-wide poster session on research.
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Angel, Cole, Trey and Rida graduated.
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Amira Reyad joined the lab for a summer internship. She was awarded a grant from Amherst, where she attends. Amira is working on visualizing what proteins exosomes colocalize with using confocal microscopy.
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Michelle received the University of Denver's Barton Weller Chair award for 2019-2022.
2018
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Michelle is awarded an NSF grant to study the role of phospholipase D in neurotransmission
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Broderick Bills, a biophysics graduate student, joins the lab.
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Aubrie Blevins, an undergraduate, was awarded PinS funding from the Undergraduate Research Center at the University of Denver. This will fund her project on Cholera Toxin B membrane binding.
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We published a paper with the Huffman Lab. Way to go Amani!
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doi: 10.1007/s00216-017-0779-7
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Michelle presented at the Colorado Single Molecule and Membranes Meeting.
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Alex Chase was awarded the Chemistry Department's Analytical Chemist of the Year award.
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At the Undergraduate Research Symposium, Alex Chase and Aubrie Blevins presented their research. Alex won third place in the poster competition and was noted to be very innovative.
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Tania Wyss joins the lab. She is working on a collaborative project with the Chapman lab at DU.
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Ronald (Trey) Berry was awarded funding from the Undergraduate Research center to perform research this summer on SNARE proteins.
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Amira Otmane was awarded the first ever Summer Undergraduate Research Fellowship from the Department of Chemistry. She will work on single molecule RNA work in collaboration with Erich Chapman's lab.
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Aubrie Blevins, Alex Chase and Je Yoo graduated!
2017
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Anarkali Mahmood joins the lab.
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Alan published his first paper with Philip Cheney and Alec Feuerbach in Membranes
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Aml Alnaas, Carrie Moon and Mitch Alton published their work on the membrane curvature sensing ability of C-reactive protein in the Journal of Physical Chemistry B.
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Michelle presented the CRP work at the Biophysical Society meeting.
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Carrie defended her dissertation work on C-reactive Protein.
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Alex Chase, an undergraduate, was awarded funding from the University of Denver Undergraduate Research Center to do research in the summer.
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Henry Cai published a collaborative paper with Prof. Scott Reed, Stephen Budy and Desmond Hamilton from University of Colorado Denver.
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doi: 10.1016/j.jcis.2016.10.022
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2016​
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Aml Alnaas defends her dissertation and graduates with a PhD.
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Carrie Moon presented a poster on her work on C-reactive protein at the University of Denver graduate student research day.
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Henry (Yuheng Cai) pubished a portion of his work in JCIS.
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Aml submitted her work on C-reactive protein for publication.
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Alan Weisgerber and Alex Chase join the lab.
2014
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Alec Feuerbach recieved funding from the Undergraduate Research Center at the University of Denver.
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Michelle gave a talk at the IEEE Colorado meeting on Gold Nanomaterials.
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Philip Cheney received a scholarship from the Chickasaw Nation.
2015
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Michelle receives an NSF - CAREER award entitled "Biosensor Development for Probing Nanoscale Topology in Neurotransmission"
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The University of Denver hosted the Colorado Single Molecule and Membranes Meeting (4th annual CSMMM), where Michelle gave a talk and Philip Cheney presented a poster.
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Carrie presented a talk at the Regional APS meeting in Arizona
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Aml Alnaas and Carrie Moon present a poster on their work on C-reactive protein at the University of Denver graduate student research day.
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Henry (Yuheng Cai) defended his thesis on "Lipid-Coated Gold Nanoparticle as a Biosensor for Lipid-Protein Interactions"
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Henry (Yuheng Cai) and Carrie Moon present posters at the National American Chemical Society meeting in Denver, Colorado.
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Mitch Alton received funding from the Undergraduate Research Center at the University of Denver for the summer.
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Michelle becomes a Marie Curie and VINNMER Fellow
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Michelle receives funding from Vinnova for her sabbatical in Sweden.
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Michelle joins Sebastian Barg's lab in the Department of Medical Cell Biology at Uppsala University for a year long sabbatical.